Friday, February 15, 2013

"Two other women, also breast cancer survivors, said their husbands left them after they were..."

Two other women, also breast cancer survivors, said their husbands left them after they were diagnosed. Both had to have mastectomies (in case anyone doesn?t know, this is the surgical operation to remove one or both breasts).

The first woman said her husband told her that he would rather see her dead than see her lose her breasts. The second woman had her operation and waited all day to be picked up by her husband, who never arrived. By nightfall, one of the nurses offered to give her a ride, and she came home to find the house empty.

Obviously, these are extreme cases of a man?s reaction to his wife?s breast cancer, but this is what I see when I see the ?I ? Boobies? bracelets. I see love of the body parts, not the person being treated?not the patient, not the victim, not the survivor.

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Source: http://twotwoonetea.tumblr.com/post/43163701404

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Vote for Tyler Eifert to be on the cover of EA Sports? NCAA Football 14!

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Source: http://www.facebook.com/blueandgoldillustrated/posts/616928955000625

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Fla. city banks on manatees after nuke plant retired

Carlos Barria / Reuters file

Manatees gather near the outlet where Florida Power & Light Company pipes warm the water at an inactive power plant undergoing renovation work in Riviera Beach, Fla., in January 2010.

By Saundra Amrhein, Reuters

CRYSTAL RIVER, Fla. - The decision earlier this month to retire a nuclear plant near this small Florida city - potentially costing hundreds of jobs and lost revenue - has residents banking on the lure of the endangered manatee.

"We'll always have tourism, we'll always have manatees. That's a huge draw," said Michele Bunts, manager of Cracker's Bar, Grill & Tiki, as employees wiped down tables in preparation for the lunch crowd on the deck overlooking the sparkling blue waters of Kings Bay, the headwaters of Crystal River.?

As the nation's only place where people can legally swim with manatees, Crystal River draws tourists from around the world for a chance to snorkel with the sea cows, which can be 10 feet long and weigh between 800 and 1,200 lbs. Tourists also enjoy the chance to spot the creatures from a boat or land.?

Bunts expects that her restaurant, a popular watering hole in this central-west Florida city of about 4,000 people, could see a decline in customers in the wake of Duke Energy Corp's announcement last week that it will retire the plant. Like many of her fellow residents, she hopes that tourists flocking to see the manatees will make up the difference in lost revenue.?

Residents will have some time to absorb the impact as the process of decommissioning the nuclear plant takes decades, said Sterling Ivey, spokesman for Progress Energy Florida, a subsidiary of Duke. "It's not like a factory where we lock the doors and everybody gets a pink slip," he said.?

The Crystal River nuclear plant had been in operation since 1977, helping serve Duke's 1.6 million Florida customers. It had already been shut down and offline since 2009 due to structural damage during upgrades to the unit's steam generators.?

About 600 people could lose their jobs once the plant is eventually retired, but there will be plenty of work for at least the next five to seven years, said Ivey. The plant would then transition into a "mothballed-type status" for another 20 to 25 years.?

The Kings Bay manatee refuge, located about 80 miles north of Tampa, lies about 8 miles south of the nuclear plant complex.?

The dozens of natural freshwater springs in the bay area are home to hundreds of manatees during winter months as the herbivorous marine mammals escape the chilly waters of the Gulf of Mexico for the 72-degree Fahrenheit warmth of the brackish sanctuary.?

Manatee mania
The manatee's importance to the town's tourist industry is on display in front of the tan-brick one-story City Hall - a star-studded replica of the mammal painted red, white and blue.?

The nuclear plant is on Duke property along with four coal-powered energy plants that are expected operate at least for the next few years.?

Duke said it was considering alternatives to replace the nuclear plant, including the construction of a new natural gas-fired plant.?

Duke is the largest employer and taxpayer in Citrus County, according to the Tampa Bay Times. Shutting the nuclear plant would lower the company's tax bill from $35 million to as little as $13 million, a loss that equals a quarter of the county's general fund, the paper reported.?

Residents worry that the closure could further depress the housing market in this rural county dotted by forest preserves, strip malls and manatee attractions.?

Store and restaurant owners were hoping to recoup lost business if Duke chose to decontaminate the plant, adding more workers. Instead, the company announced on Feb. 5 it planned to pursue another option, safely storing the plant for several decades to let nature help with the decay before cleaning out the rest of the radiation.?

Crystal River Mayor Jim Farley acknowledged that the county as a whole might take a hit should many employees be reassigned out-of-state and if property tax income drops if Duke does not replace the nuclear facility with a natural gas plant.?

But he predicted that ongoing plans for the springs will make the area a bigger ecotourism attraction than it already is.?

"It's not going to be a disaster," Farley said. "I think we're going to be able to cope. We'll lose some business because of it, probably. These are tough economic times as it is, but we have so much going for us."?

Long-term residents roll their eyes at the promises of city-sponsored development of ecotourism. Officials have been saying that for years, said Greg Dristiliaris, deli manager at a Shell gas station.?

Plant workers once packed the place in the mornings to buy lunch sandwiches and in late afternoons after work to buy food, beer, cigarettes or tobacco, he said. He used to have 30-40 pizzas on hand to sell each day, he said. Now he does not offer pizzas at all.?

Like the others, Dristiliaris said the most challenging part of the news is the uncertainty of what comes next. But as a long-time Floridian, he compared coping with tumultuous change to another familiar part of life in Florida - hurricanes.?

"You just got to roll with it," he said.?

Copyright 2013 Thomson Reuters. Click for restrictions.

Source: http://usnews.nbcnews.com/_news/2013/02/14/16962212-florida-city-hopes-manatees-fill-economic-void-left-by-retired-nuclear-plant?lite

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Thursday, February 14, 2013

Report: Tracking system needed to fight fake drugs

WASHINGTON (AP) ? Fighting the problem of fake drugs will require creating a national drug-tracking system, the Institute of Medicine said Wednesday.

The call for putting medications through a chain of custody like U.S. courts require for evidence in a trial comes a week after the Food and Drug Administration warned doctors, for the third time in about a year, that it discovered a counterfeit batch of the cancer drug Avastin that lacked the real tumor-killing ingredient.

Fake and substandard drugs have become an increasing concern as U.S. pharmaceutical companies move more of their manufacturing overseas. The risk made headlines in 2008 when U.S. patients died from a contaminated blood thinner imported from China.

The Institute of Medicine report made clear that this is a global problem that requires an international response, with developing countries especially at risk from phony medications. Drug-resistant tuberculosis, for example, is fueled in part by watered-down medications sold in many poor countries.

"There can be nothing worse than for a patient to take a medication that either doesn't work or poisons the patient," said Lawrence O. Gostin, a professor of health law at Georgetown University who led the IOM committee that studied how to combat the growing problem.

A mandatory drug-tracking system could use some form of barcodes or electronic tags to verify that a medication and the ingredients used to make it are authentic at every step, from the manufacturing of the active ingredient all the way to the pharmacy, he said. His committee examined fakes so sophisticated that health experts couldn't tell the difference between the packaging of the FDA-approved product and the look-alike.

"It's unreliable unless you know where it's been and can secure each point in the supply chain," Gostin said.

Patient safety advocates have pushed for that kind of tracking system for years, but attempts to include it in FDA drug-safety legislation last summer failed.

The report also concluded that:

?The World Health Organization should develop an international code of practice that sets guidelines for monitoring, regulation and law enforcement to crack down on fake drugs.

?States should step up licensing requirements for the wholesalers and distributors who get a drug from its manufacturer to the pharmacy, hospital or doctor's office.

?Internet pharmacies are a particularly weak link because fraudulent sites can mimic legitimate ones. The report urged wider promotion of the National Association of Boards of Pharmacy's online accreditation program as a tool to help consumers spot trustworthy sites.

FDA Commissioner Margaret Hamburg didn't comment on the tracking system proposal but the agency already had begun some steps to better address the issue, including improving surveillance.

The Institute of Medicine is an independent organization that advises the government on health matters.

Source: http://news.yahoo.com/report-tracking-system-needed-fight-fake-drugs-145011922.html

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LinkedIn CEO Jeff Weiner Pulls An Oprah, Gives Every Employee An iPad Mini

croppedoprahTechnology is a wonderful thing, especially when your employer hooks you up with gadgets for free. Today, we’ve learned that LinkedIn has decided to give all of its employees an iPad mini. This reminds us of Oprah Winfrey giving things to her audience and exclaiming “You get an iPad, you get an iPad!” A spokesperson from LinkedIn confirmed this for us, as it’s not something that you’d want to report if it weren’t true. Employees could have gotten sad. We wanted to acknowledge the hard work and accomplishments of all of our employees in 2012. During today?s bi-weekly All Hands meeting, we surprised our employees with iPad Minis as a small gesture of the company?s gratitude for their contributions. Here’s a look at CEO Jeff Weiner standing with a whole bunch of them: The gifts were given out because the company had such a great 2012, “beating the streets” consistently in each quarter. The company currently has 3,500 employees, so if each costs $329, that’s $1,151,500.00. Someone at Apple is smiling. I wonder if they got a discount? In direct response, or not, we’re told by a source that every Intel R&D engineer just got a fully specced out Lenovo Yoga at $1,500 a pop. I’ll take the iPad, thank you.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/ZsjJsMTpLEQ/

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Identification of abnormal protein may help diagnose, treat ALS and frontotemporal dementia

Identification of abnormal protein may help diagnose, treat ALS and frontotemporal dementia

Wednesday, February 13, 2013

Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, and frontotemporal dementia (FTD) are devastating neurodegenerative diseases with no effective treatment. Researchers are beginning to recognize ALS and FTD as part of a spectrum disorder with overlapping symptoms. Now investigators reporting online February 12 in the Cell Press journal Neuron have discovered an abnormal protein that first forms as a result of genetic abnormalities and later builds up in the brains of many patients with either disease.

"In identifying the novel protein that abnormally accumulates in the brains of affected patients, we have uncovered a potentially new therapeutic target and biomarker that would allow clinicians to confirm diagnosis of the diseases," says senior author Dr. Leonard Petrucelli, Chair of Neuroscience at Mayo Clinic in Florida.

By analyzing brain tissue from patients with ALS or FTD, Dr. Petrucelli and his team discovered that the abnormal protein, which they call C9RANT, is generated as a result of repeat expansions of nucleotides in the noncoding region of the C9ORF72 gene. These expansions are the most common cause of ALS and FTD. "Simply put, an error in the highly regulated cellular process through which proteins are generated causes the abnormal production of C9RANT," explains Dr. Petrucelli.

The researchers discovered the protein C9RANT after creating a novel antibody to specifically detect it. The ability to detect C9RANT in individuals' cerebrospinal fluid may provide a valuable diagnostic and prognostic tool for identifying patients carrying the C9ORF72 repeat expansion and for then tracking the progression of the disease in these at-risk individuals.

"Although it remains to be shown whether C9RANT is causing the cell death or toxicity associated with disease symptoms, our discovery offers a potential target to prevent neuronal loss in patients carrying the C9ORF72 repeat expansion," says Dr. Petrucelli.

The concept that abnormal proteins accumulate and can be toxic to cells is not new. In fact, tau protein forms tangles in Alzheimer's disease and alpha-synuclein forms clumps in Parkinson's disease. Just as new therapies are being developed to break down the protein aggregates associated with these diseases, developing a therapeutic strategy to target C9RANT aggregates may also prove beneficial.

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Cell Press: http://www.cellpress.com

Thanks to Cell Press for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/126761/Identification_of_abnormal_protein_may_help_diagnose__treat_ALS_and_frontotemporal_dementia

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Rights groups: Zimbabwe police intensify clampdown

HARARE, Zimbabwe (AP) ? Rights groups on Tuesday said police in Zimbabwe have intensified a clampdown on civil society organizations and democracy campaigners ahead of a referendum on a new constitution and crucial elections to end the nation's shaky coalition government dominated by President Robert Mugabe's party.

Crisis in Zimbabwe, an alliance of rights groups, said police raided the offices of one of its member organizations on Monday and seized files on political violence, funding details, DVD display materials, mobile phones and other equipment. Officials of the widely respected Zimbabwe Peace Project were accused of illegal importation of goods and "possessing articles for criminal use."

No one was arrested. The officials deny any wrongdoing.

The search warrant for the peace project's offices in suburban southern Harare said the detectives were looking for "subversive material, documents, gadgets, recordings and illegal immigrants."

The police suspected the project had employed an immigrant staff member without a work permit and also smuggled unspecified goods into the country without paying customs duty, Crisis in Zimbabwe said. Police said they would study the items they had seized.

Crisis in Zimbabwe said Tuesday that Mugabe party hardliners and loyalists were still trying to scuttle democratic reforms by closing in on rights campaigners.

The Zimbabwe Human Rights Association director Okay Machisa was arrested on Jan. 14 on fraud and forgery charges involving possession of unauthorized election materials. Two other members of his staff were also detained on similar charges. ZimRights, one of Zimbabwe's main rights groups, routinely monitors political violence, intimidation and voting practices.

The Heal Zimbabwe Trust, a sister group, described the continued persecution of human rights defenders as "clearly meant to daunt and instill fear" in civil society activists despite proposed reforms in the new constitution that call for impartiality by police and security officials.

The clampdown on rights leaders "then raises concerns how safe ordinary citizens are in the face of upcoming elections," the trust said.

The 160-page draft constitution is set to be put to the vote in a referendum as early as April, followed by presidential and parliament polls possibly three months later.

On Wednesday, Zimbabwe marks the fourth anniversary of the formation of the coalition between Mugabe and Prime Minister Morgan Tsvangirai in 2009. The power sharing deal was brokered by regional leaders after disputed and violent elections in 2008.

Source: http://news.yahoo.com/rights-groups-zimbabwe-police-intensify-clampdown-112537059.html

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